Functionalized Synthetic Biodegradable Polymer Scaffolds for Tissue Engineering
نویسندگان
چکیده
منابع مشابه
Functionalized synthetic biodegradable polymer scaffolds for tissue engineering.
Scaffolds (artificial ECMs) play a pivotal role in the process of regenerating tissues in 3D. Biodegradable synthetic polymers are the most widely used scaffolding materials. However, synthetic polymers usually lack the biological cues found in the natural extracellular matrix. Significant efforts have been made to synthesize biodegradable polymers with functional groups that are used to couple...
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The field of tissue engineering places complex demands on the materials it uses. The materials chosen to support the intricate processes of tissue development and maintenance need to have properties which serve both the bulk mechanical and structural requirements of the target tissue, as well as enabling interactions with cells at the molecular scale. In this critical review we explore how synt...
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Critical size bone defects due to trauma or disease are very difficult to repair via the natural growth of the host bone. Therefore, these defects must be filled with a bridging material (scaffold), which should also, in combination with relevant cells and signalling molecules, promote the regeneration of new bone tissue. In this context, bone regeneration is one of the most attractive areas in...
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This paper reviews biodegradable synthetic polymers focusing on their potential in tissue engineering applications. The major classes of polymers are briefly discussed with regard to synthesis, properties and biodegradability, and known degradation modes and products are indicated based on studies reported in the literature. A vast majority of biodegradable polymers studied belongs to the polye...
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Background: The aim of this study was to fabricate the poly caprolactone (PCL) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (HFSC) in the graft material using electrospun PCL nanofiber scaffold for tissue engineering applications. Methods: The bulge region of rat whisker was isolated and cultured in DMEM: n...
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ژورنال
عنوان ژورنال: Macromolecular Bioscience
سال: 2012
ISSN: 1616-5187
DOI: 10.1002/mabi.201100466